A multi-agency team co-ordinated by Genomics Aotearoa is exploring the rapidly advancing science of genetic-based control for developing crucial new rat suppression technology. This is a crucial collaboration, given New Zealand’s current approaches are insufficient to achieve PF2050 rat eradication targets.
This builds on the first ship rat genome already sequenced by New Zealand researchers with support from the first Predator Free 2050 Ltd Research Strategy (2017-20).
Brooke Whitelaw is involved in a postdoctoral research project that aims to address the issue of invasive rat populations threatening native bird species in Aotearoa (New Zealand).
Through their expertise in genetics and bioinformatics, Brooke is studying the genetic structure of these rat populations, aiming to provide insights that can contribute to effective management strategies.
In particular, they are performing whole-genome resequencing of 200 rat genomes to discover how Norway and ship rats move across Aotearoa.
Understanding movement patterns and genetic diversity within rat populations will allow the generation of a more targeted elimination framework. This is crucial to elimination efforts as repopulation of a previously pest-free area is increasingly becoming an issue.
Additionally, they will also be looking for genes that can be used as targets for what is termed gene drive technology. This involves manipulating a gene usually affecting fertility; in this way, we can inhibit reproduction leading to the natural death of populations as no future generations are produced.
About Brooke
Brooke started their journey by pursuing a degree in Wildlife Conservation Biology, where they developed a solid understanding of the field.
Captivated by the wonders of nature, they became particularly interested in the evolution of venomous creatures during their honour’s year, where they compared the proteins within the venom gland of two octopods, the southern sand octopus and the southern blue-ringed octopus.
Continuing the scientific exploration, Brooke embarked on an industry project centred on yellow-tailed kingfish populations. This project aimed to inform management decisions between different states of Australia, and they played a key role in conducting DNA extractions and PCR amplifications to unravel the population genetic structures among different regions.
Driven by curiosity and desire to make a meaningful impact, Brooke then pursued a PhD in Genetics/Bioinformatics. Their research focused on understanding the genome evolution of octopods, with a particular emphasis on the southern blue-ringed octopus. They made notable contributions to the field by creating the first genetic linkage map for a cephalopod and exploring the genetic relationships within the blue-ringed octopus species complex.
This has now progressed to the current post doctoral research. “I’m enjoying this aspect of the work because it allows me to apply the skills I gained during my PhD to a conservation project,” they said.